What are the side effects of Testosterone Enanthate?

Testosterone enanthate

In addition, Almukhtar et al. reported that the kidney tissues of four bodybuilders who used more than 400 mg of testosterone propionate in a week showed tubular necrosis and increased kidney inflammation (13). Apoptosis, an influential factor in developing kidney fibrosis, can be triggered by various inflammatory cytokines (14). Androgens also play an essential role in the induction of apoptosis. For example, androgens can induce kidney cell apoptosis by inducing a caspase-dependent apoptotic pathway (15). Also, testosterone can induce the production of pro-inflammatory cytokines such as tumor necrosis factor-alpha (TNF-α) and interleukin-6 (IL-6), leading to renal inflammation and CKD progression (16). Testosterone replacement therapy (TRT) is a medical intervention designed to supplement or restore the body’s natural testosterone levels.

Tell your health care provider if you or your bed partner notices that you have symptoms such as snoring, sleepiness during the day, restless sleeping, or waking up suddenly after gasping or choking. Testosterone can cause fluid retention, also called edema. Fluid retention can cause serious issues in people with certain conditions, such as heart failure or kidney problems. Call your health care provider right away if you have any of the following symptoms.

Your doctor will order certain lab tests to check your testosterone levels to see if they are low before you begin to use testosterone injection. Testosterone enanthate (available generically) and testosterone pellet (Testopel) are also used to stimulate puberty in males with delayed puberty. Testosterone enanthate (available generically) injection may be used in certain women with a type of breast cancer called mammary cancer that has spread to other parts of the body. Testosterone should not be used to treat the symptoms of low testosterone in men who have low testosterone due to aging (‘age related hypogonadism’). Testosterone is in a class of medications called androgenic hormones. Testosterone is a hormone produced by the body that contributes to the growth, development, and functioning of the male sexual organs and typical male characteristics. Testosterone injection works by supplying synthetic testosterone to replace the testosterone that is normally produced naturally in the body.

Both esters are long-acting injectable forms of testosterone, designed to maintain stable hormone levels over time. However, Cypionate has a slightly longer half-life than Enanthate—approximately 8 to 12 days vs. 8 to 10 days. Testosterone Cypionate has a slightly longer half-life (8–12 days) compared to Enanthate, which can be advantageous for those preferring fewer injections. The extended release profile supports stable serum testosterone levels, reducing peaks and troughs and offering a smoother hormonal experience (Morgentaler, 2022). Work closely with a healthcare provider, track your response over time, and stay consistent with your protocol. Both compounds are powerful tools—what matters most is how your body responds and how your treatment aligns with your goals and lifestyle. Among the different forms of synthetic testosterone available, Testosterone Enanthate and Testosterone Cypionate are two of the most widely used esters.

This drug is banned from use in athletes by most athletic organizations. Testosterone propionate is metabolized faster due to its less polar chemical nature and is not available for longer absorption periods. Consulting with a healthcare professional who specializes in hormone replacement therapy is crucial for developing a personalized treatment plan that aligns with your specific needs. Regular monitoring of testosterone levels, adherence to the prescribed dosing schedule, and addressing any potential side effects are important aspects of successful testosterone replacement therapy. By working closely with a healthcare provider, individuals can optimize their testosterone levels and achieve their desired outcomes. A study by Castaneda et al. clarified that moderate resistance training reduced the levels of inflammatory factors in the kidney tissue (17).

Testosterone enanthate and Xyosted are injections used to treat hypogonadism, testosterone deficiencies, and FTM transition, but differ in dosage and frequency. Take our online test and check if you are eligible for our hormone therapy. This allows our medical team to analyse your blood test and confirm if you’ve qualified for treatment.

Dr. Gulzar has been working in medical communications, writing medical and clinical research for patients and health professionals in the United Kingdom. Testosterone enanthate injection contains testosterone, a Schedule III controlled substance in the Controlled Substances Act. Testosterone is a controlled substance because it can be misused or lead to dependence. Store testosterone in a safe place to protect it from theft. Certain testosterone injectable products may also be used as part of breast cancer treatment. Testosterone can affect bone growth in boys who are treated for delayed puberty. Bone development may need to be checked with x-rays every 6 months during treatment.

Testosterone therapy is one of the main treatments for male children who experience delayed puberty. A 2019 review notes that testosterone therapy has become increasingly popular in the United States. Prescriptions of testosterone for males over 60 years of age quadrupled from 2001 to 2011. Both Testosterone Enanthate and Cypionate are delivered through intramuscular injection, most commonly in the gluteal muscles or vastus lateralis (thigh). Because of its slightly longer ester, Cypionate may require fewer injections, though both are typically dosed every 7 to 10 days for therapeutic use.

Like Cypionate, Testosterone Enanthate is also typically administered every 1-2 weeks. Since it offers a reliable and consistent release profile, it is widely used in TRT to achieve steady testosterone levels. When comparing Testosterone Enanthate and Testosterone Cypionate, one of the most practical considerations is injection frequency.

The medication will work in your body the same way regardless of taking it subq or intra. Empower Pharmacy is the nation’s largest, most advanced 503A compounding pharmacy and 503B outsourcing facility. Our mission is test boost max safe (mceditrice.it) to provide access to the best compound medication solutions for patients, practitioners, and pharmacies.